Our high-impact and interdisciplinary research.


DNA, Peptide,
Natural Polyphenols (?)

Superstructured mesocrystals through multiple inherent molecular interactions for highly reversible sodium ion batteries

Qiu et al., Science Advances 2021

Selected publications in high-rank journals

(*) Corresponding author

Near infrared light-induced dynamic modulation of enzymatic activity through polyphenol-functionalized liquid metal nanodroplets.

Chaojun Zhang, Yang Tang, Qin Wang, Yunxiang He, Xiaoling Wang*, Sebastian Beyer, Junling Guo*

Chinese Chemical Letters, (2022)


Microporous membranes for ultrafast and energy-efficient removal of antibiotics through polyphenol-mediated nanointerfaces.

Yu Wang, Yunxiang He, Qin Wang, Xiaoling Wang*, Blaise L. Tardy, Joseph J. Richardson, Orlando J. Rojas, Junling Guo*

Matter, (2022)


A single-cell nanocoating of probiotics for enhanced amelioration of antibiotic-associated diarrhea.

Jiezhou Pan, Guidong Gong, Qin Wang, Jiaojiao Shang, Yunxiang He, Chelsea Catania, Dan Birnbaum, Yifei Li, Zhijun Jia, Yaoyao Zhang*, Neel S. Joshi*, Junling Guo*

Nature Communications, (2022)


Intratumoral synthesis of transformable metal-phenolic nanoaggregates with enhanced tumor penetration and retention for photothermal immunotherapy.

Xianglian He, Hongfu Zhu, Jiaojiao Shang, Meifeng Li, Yaoyao Zhang, Shicheng Zhou, Guidong Gong*, Yunxiang He*, Anna Blocki, Junling Guo*

Theranostics, (2022)


Driving forces and molecular interactions in the self-assembly of block copolymers to form fiber-like micelles

Yunxiang He, Yang Tang, Yifan Zhang, Liam MacFarlane, Jiaojiao Shang, Heping Shi, Qiuping Xie, Hui Zhao*, Ian Manners, Junling Guo*

Applied Physics Reviews, (2022)


Biomass-based encapsulating material for probiotic protection and methods of use thereof


Junling Guo, Yaoyao Zhang, Jiezhou Pan, Guidong Gong

US Patent App., (2022)


The role of extracellular matrix on unfavorable maternal–fetal interface: focusing on the function of collagen in human fertility

Rang Liu, Mengyuan Dai, Guidong Gong, Mei Chen, Canhui Cao, Tianren Wang, Zhenhui Hou, Yu Shi, Junling Guo*, Yaoyao Zhang*, Xi Xia*

Journal of Leather Science and Engineering, (2022)


Collagen-based materials in reproductive medicine and engineered reproductive tissues

Hanxiao Chen, Luqi Xue, Guidong Gong, Jiezhou Pan, Xiaoling Wang, Yaoyao Zhang*, Junling Guo*, Lang Qin*

Journal of Leather Science and Engineering, (2022)

Nanostructured particles assembled from natural building blocks for advanced therapies
Yi Ju, Haotian Liao, Joseph J Richardson,
Junling Guo*, Frank Caruso*
Chemical Society Review, (2022)
Invited Review

Alloyed nanostructures integrated metal-phenolic nanoplatform for synergistic wound disinfection and revascularization
Yi Xie, Shengqiu Chen, Xu Peng, Xiaoling Wang, Zhiwei Wei, Joseph  J. Richardson, Kang Liang, Hirotaka Ejima,
Junling Guo*, Changsheng Zhao*
Bioactive Materials, (2022)

Engineering microparticles based on solidified stem cell secretome with an augmented pro-angiogenic factor portfolio for therapeutic angiogenesis
Thomas Später, Marisa Assunção, Kwok Keung Lit, Guidong Gong, Xiaoling Wang, Yi-Yun Chen, Ying Rao, Yucong Li, Chi Him Kendrick Yiu, Matthias W Laschke, Michael D Menger, Dan Wang, Rocky S Tuan, Kay-Hooi Khoo, Michael Raghunath,
Junling Guo*, Anna Blocki*
Bioactive Materials, (2022)

Imparting reusable and SARS-CoV-2 inhibition properties to standard masks through metal-organic nanocoatings
Xiaoling Wang#, Ting Hu#, Bing Hu, Yan Liu, Yu Wang, Yunxiang He, Yan Li, Kun Cai*, Xingcai Zhang*,
Junling Guo*
Journal of Hazardous Materials, (2022)

Natural polyphenol-based nanoengineering of collagen-constructed hemoperfusion adsorbent for the excretion of heavy metals
Meifeng Li, Xiaoling Wang, Guidong Gong, Yi Tang, Yaoyao Zhang,
Junling Guo*, Xuepin Liao*, Bi Shi
Journal of Hazardous Materials, (2022)

Self-assembly of nanomicelles with rationally designed multifunctional building blocks for synergistic chemo-photodynamic therapy
Guidong Gong, Jiezhou Pan, Yunxiang He, Jiaojiao Shang, Xiaoling Wang, Yaoyao Zhang, Guolin Zhang, Fei Wang*, Gang Zhao*,
Junling Guo*
Theranostics, (2022)

Modular biohybrid systems and methods of use thereof

Junling Guo, Miguel Suastegui, Neel S. Joshi
US Patent App., (2021)

Superstructured mesocrystals through multiple inherent molecular interactions for highly reversible sodium-ion batteries

Xiaoling Qiu#, Xiaoling Wang#, Yunxiang He#, Jieying Liang, Kang Liang, Blaise L. Tardy, Joseph J. Richardson, Ming Hu, Hao Wu, Yun Zhang, Orlando J. Rojas, Ian Manners, Junling Guo*
Science Advances, (2021)

Biofilms in plant-based fermented foods: Formation mechanisms, benefits and drawbacks on quality and safety, and functionalization strategies

Chuanjie Gong, Yunxiang He, Yao Tang, Rong Hu, Yuanping Lv, Qisheng Zhang, Blaise L Tardy, Joseph J Richardson, Qiang He, Junling Guo*, Yuanlong Chi*
Trends in Food Science & Technology, (2021)

Systemic tumour suppression via the preferential accumulation of erythrocyte-anchored chemokine-encapsulating nanoparticles in lung metastases

Zongmin Zhao, Anvay Ukidve, Vinu Krishnan, Alexandra Fehnel, Daniel C. Pan, Yongsheng Gao, Jayoung Kim, Michael A. Evans, Abhirup Mandal, Junling Guo, Vladimir R. Muzykantov, Samir Mitragotri*
Nature Biomedical Engineering, (2021)

A Heterostructure-In-Built Multichambered Host Architecture Enabled by Topochemical Self-Nitridation for Rechargeable Lithiated Silicon-Polysulfide Full Battery

Yunhong Wei, Mi Zhang, Li Yuan, Boya Wang, Hongmei Wang, Qian Wang, Yun Zhang*, Junling Guo*, Hao Wu*
Advanced Functional Materials, (2021)

Skin-inspired gelatin-based flexible bio-electronic hydrogel for wound healing promotion and motion sensing
Manhui Zheng, Xuechuan Wang*, Ouyang Yue, Mengdi Hou, Huijie Zhang, Sebastian Beyer, Anna Maria Blocki, Qin Wang, Guidong Gong, Xinhua Liu*, Junling Guo*
Biomaterials, (2021)

Engineered Liver-Inspired Collagen Matrix as a High-Performance Hemoperfusion Adsorbent for Bilirubin Removal
Meifeng Li, Xiaoling Wang, Guidong Gong, Xia Li, Yi Tang, Qin Wang, Jibo Zhou, Junling Guo*, Xuepin Liao*, Bi Shi
Chemical Engineering Journal, (2021)

Thermoresponsive Hemostatic Hydrogel with a Biomimetic Nanostructure Constructed from Aggregated Collagen Nanofibers
Xinhua Liu*, Mengdi Hou, Xiaomin Luo, Manhui Zheng, Xuechuan Wang*, Huijie Zhang, Junling Guo*
Biomacromolecules, (2021)

Rapid Assembly of Colorless Antimicrobial And Anti-Odor Coatings From Polyphenols And Silver
Joseph J Richardson, Wenting Liao, Jincai Li, Bohan Cheng, Chenyu Wang, Taku Maruyama, Blaise L Tardy,
Junling Guo, Lingyuan Zhao, Wanping An, Hirotaka Ejima
Scientific Reports, (2021)

Hyaluronic a cid–doxorubicin nanoparticles for targeted treatment of colorectal cancer
Daniel C Pan, Vinu Krishnan, Alyssa K Salinas, Jayoung Kim, Tao Sun, Sagi Ravid, Kevin Peng, Debra Wu, Md Nurunnabi, Jeffery A Nelson, Zachary Niziolek,
Junling Guo, Samir Mitragotri*
Bioengineering & Translational Medicine, (2021)

Collagen peptide provides Streptomyces coelicolor CGMCC 4.7172 with abundant precursors for enhancing undecylprodigiosin production
Xia Li, Meifeng Li,
Junling Guo, Xian Liu, Xuepin Liao*, Bi Shi
Journal of Leather Science and Engineering, (2021)

Engineering of Living Cells with Polyphenol-Functionalized Biologically Active Nanocomplexes

Zongmin Zhao, Daniel C. Pan, Qin M. Qi, Jayoung Kim, Neha Kapate, Tao Sun, C. Wyatt Shields IV, Lily Li-Wen Wang, Debra Wu, Christopher J. Kwon, Wei He, Junling Guo*, Samir Mitragotri*
Advanced Materials, (2020)

Lightweight and Wearable X‐Ray Shielding Material with Biological Structure for Low Secondary Radiation and Metabolic Saving Performance
Yaping Wang, Rui Zhong, Qian Li, Jiali Liao, Ning Liu, Neel S Joshi, Bi Shi, Xuepin Liao*, Junling Guo*
Advanced Materials Technologies, (2020)
Profited by:
- Science: Highlighted Article coming
Fédération des Sociétés Scientifiques: Highlighted Article coming
- ONISEP: Highlighted Article coming

Nanocarrier‐Mediated Cytosolic Delivery of Biopharmaceuticals
Wei He, Xuyang Xing, Xiaoling Wang, Debra Wu, Wei Wu, Junling Guo*, Samir Mitragotri*
Advanced Functional Materials, (2020)  - Invited Review

Layered Self-Assemblies for Controlled Drug Delivery: A Translational Overview
Apoorva Sarode, Akshaya Annapragada, Junling Guo, Samir Mitragotri*
Biomaterials, (2020)

Exploiting Supramolecular Interactions from Polymeric Colloids for Strong Anisotropic Adhesion between Solid Surfaces
Blaise L. Tardy, Joseph J. Richardson, Luiz G. Greca, Junling Guo, Hirotaka Ejima*, Orlando J. Rojas*
Advanced Materials, (2020)  - Cover Article
Hierarchical assembly of nanostructured coating for siRNA-based dual therapy of bone regeneration and revascularization
Helin Xing, Xing Wang, Gao Xiao, Zongmin Zhao, Shiquan Zou, Man Li, Joseph J Richardson, Blaise L Tardy, Liangxia Xie, Satoshi Komasa, Joji Okazaki, Qingsong Jiang*, Guodong Yang*, Junling Guo*
Biomaterials, (2020)

Engineering robust metal–phenolic network membranes for uranium extraction from seawater
Wei Luo, Gao Xiao, Fan Tian, Joseph J Richardson, Yaping Wang, Jianfei Zhou, Junling Guo*, Xuepin Liao*, Bi Shi
Energy & Environmental Science, (2019) - Cover Article

Unidirectional presentation of membrane proteins in nanoparticle‐supported liposomes
Wen Chen, Yongfei Cai, Qingshan Fu, Bing Chen, Junling Guo*, James Jeiwen Chou*
Angewandte Chemie International Edition, (2019) - Cover Article

Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin
Ke Li, Gao Xiao, Joseph J Richardson, Blaise L Tardy, Hirotaka Ejima, Wen Huang, Junling Guo*, Xuepin Liao*, Bi Shi
Advanced Science, (2019) - Cover Article

Self‐Assembled Metal‐Phenolic Nanoparticles for Enhanced Synergistic Combination Therapy against Colon Cancer
Ke Li, Yunlu Dai, Wen Chen, Kang Yu, Gao Xiao, Joseph J Richardson, Wen Huang, Junling Guo*, Xuepin Liao, Bi Shi
Advanced Biosystems, (2019) - Cover Article

Metal-dependent inhibition of amyloid fibril formation: synergistic effects of cobalt–tannic acid networks
Wenjie Zhang, Andrew J Christofferson, Quinn A Besford, Joseph J Richardson, Junling Guo, Yi Ju, Kristian Kempe, Irene Yarovsky*, Frank Caruso*
Nanoscale, (2019)

Modular Assembly of Biomaterials Using Polyphenols as Building Blocks
Junling Guo*, Tomoya Suma, Joseph J Richardson, Hirotaka Ejima*
ACS Biomaterials Science & Engineering(2019)
Invited Review - "Japanese Biomaterials Special Issue"

Light-driven fine chemical production in yeast biohybrids
Junling Guo*, Miguel Suástegui, Kelsey K Sakimoto, Vanessa M Moody, Gao Xiao, Daniel G Nocera, Neel S Joshi*
Science, (2018)
(Profited by:
- Nano Today: Highlighted Article coming;
- Nature Biotechnology: Research Highlights “Yeast solar panels”;
- Eurekalert/AAAS: Solar panels for yeast cell biofactories;
- Harvard Gazette: Yeast are getting a boost from solar power;
- Phys.org: Solar panels for yeast cell biofactories;
- NRC.nl: Supergist krijgt energie van eigen ‘zonnecollectoren’;
- The Scientist: Solar-Powered Yeast Are More Efficient Drug Factories;

Porous Inorganic and Hybrid Systems for Drug Delivery: Future Promise in Combatting Drug Resistance and Translation to Botanical Applications
Junling Guo, Bruno D. Mattos, Blaise L. Tardy, Vanessa M. Moody, Gao Xiao, Hirotaka Ejima, Jiwei Cui, Kang Liang, Joseph Jacob Richardson
Current Medicinal Chemistry, (2018) - Invited Review

Lignin Nano- and Microparticles as Template for Nanostructured Materials: Formation of Hollow Metal-Phenolic Capsules
Blaise Leopold Tardy, Joseph Jacob Richardson, Junling Guo, Janika Lehtonen, Mariko Ago, Orlando J. Rojas*
Green Chemistry, (2018)

Probing Transcription Factor Binding Activity and Downstream Gene Silencing in Living Cells with a DNA Nanoswitch
Alessandro Bertucci, Junling Guo, Nicolas Oppmann, Agata Glab, Francesco Ricci, Frank Caruso*, Francesca Cavalieri*
Nanoscale, (2018)

Synthesis of Metal Nanoparticles in Metal‐Phenolic Networks: Catalytic and Antimicrobial Applications of Coated Textiles
Gyeongwon Yun, Shuaijun Pan, Ting‐Yi Wang, Junling Guo, Joseph J Richardson, Frank Caruso*
Advanced Healthcare Materials, (2017)

Influence of ionic strength on the deposition of metal–phenolic networks
Junling Guo, Joseph J Richardson, Quinn A Besford, Andrew J Christofferson, Yunlu Dai, Chien W Ong, Blaise L Tardy, Kang Liang, Gwan H Choi, Jiwei Cui, Pil J Yoo, Irene Yarovsky*, Frank Caruso*
Langmuir, (2017)

Self‐Assembled Nanoparticles from Phenolic Derivatives for Cancer Therapy
Yunlu Dai, Junling Guo, Ting‐Yi Wang, Yi Ju, Andrew J Mitchell, Thomas Bonnard, Jiwei Cui, Joseph J Richardson, Christoph E Hagemeyer, Karen Alt*, Frank Caruso*
Advanced Healthcare Materials, (2017)

Modular assembly of superstructures from polyphenol-functionalized building blocks
Junling Guo, Blaise L Tardy, Andrew J Christofferson, Yunlu Dai, Joseph J Richardson, Wei Zhu, Ming Hu, Yi Ju, Jiwei Cui, Raymond R Dagastine, Irene Yarovsky, Frank Caruso*
Nature Nanotechnology, (2016)
(Profited by:
- Nature Nanotechnology, Kotov, N. A, Particle self-assembly: Superstructures simplified;
- Nature Biotechnology, Research Highlights, 34, 1129, 2016;
- GIZMODO: “Australian Scientists Just Invented Nanoscale LEGO”;
- IChemE: “LEGO coating offers nano-engineering method”;
- Nanotechweb.org: “Polyphenol helps superstructure nano-objects”;
- Nanotech-Now: “Nanoscale engineering transforms particles into 'LEGO-like' building blocks”;
- Chemeurope: “Nanoscale engineering transforms particles into 'LEGO-like' building blocks”;
- Lab+Life Scientists: “Tiny particles transformed into Lego-like building blocks”;
- Technology.org: “Nanoscale engineering transforms particles into “LEGO-like” building blocks”
- CEN Magazines: “Nanoscale Engineering Creates LEGO-like Building Blocks”;
- ECN: “Nanoscale Engineering Transforms Particles Into 'LEGO-Like' Building Blocks”;
- Eurekalert!: “Nanoscale engineering transforms particles into 'LEGO-like' building blocks”;
- Phys.org: “Nanoscale engineering transforms particles into 'LEGO- like' building blocks”;

Controlling the growth of metal‐organic frameworks using different gravitational forces
Joseph J Richardson, Kang Liang, Fabio Lisi, Mattias Björnmalm, Matthew Faria, Junling Guo, Paolo Falcaro
European Journal of Inorganic Chemistry, (2016)
(Profited by:
- Video Abstracts: ChemistryViews; Researchers Take Materials Science to New Heights
- ChemViews Magazine: Skydiving Helps Understand MOFs
- Science: Taking a break is hard work, too, 2019, DOI: 10.1126/science.364.6435.98
- Lactualitechimique.org: La chimie, science de l’extrême!
- science.casual: Chemistry takes a dive
Polymer Capsules for Plaque‐Targeted In Vivo Delivery
Joseph J Richardson, Mei Y Choy, Junling Guo, Kang Liang, Karen Alt, Yuan Ping, Jiwei Cui, Lok S Law, Christoph E Hagemeyer, Frank Caruso*
Advanced Materials, (2016)

pH‐Responsive Capsules Engineered from Metal–Phenolic Networks for Anticancer Drug Delivery
Yuan Ping, Junling Guo, Hirotaka Ejima, Xi Chen, Joseph J Richardson, Huanli Sun, Frank Caruso
Small, (2015)

Versatile loading of diverse cargo into functional polymer capsules
Joseph J Richardson, James W Maina, Hirotaka Ejima, Ming Hu, Junling Guo, Mei Y Choy, Sylvia T Gunawan, Lien Lybaert, Christoph E Hagemeyer, Bruno G De Geest, Frank Caruso*
Advanced Science, (2015) - Cover Article

Nanoporous Metal–Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide
Junling Guo, Xiaowei Wang, Darren C Henstridge, Joseph J Richardson, Jiwei Cui, Arpeeta Sharma, Mark A Febbraio, Karlheinz Peter, Judy B de Haan, Christoph E Hagemeyer, Frank Caruso*
Advanced Healthcare Materials, (2015)
Boronate–Phenolic Network Capsules with Dual Response to Acidic pH and cis‐Diols
Junling Guo, Huanli Sun, Karen Alt, Blaise L Tardy, Joseph J Richardson, Tomoya Suma, Hirotaka Ejima, Jiwei Cui, Christoph E Hagemeyer, Frank Caruso*
Advanced Healthcare Materials, (2015)
The role of capsule stiffness on cellular processing
Huanli Sun, Edgar HH Wong, Yan Yan, Jiwei Cui, Qiong Dai, Junling Guo, Greg G Qiao, Frank Caruso*
Chemical Science, (2015)

Synergistic Enhancement of Lung Cancer Therapy Through Nanocarrier‐Mediated Sequential Delivery of Superantigen and Tyrosin Kinase Inhibitor Authors Da Li, Yongbin Li, Haibo Xing, Junling Guo, Yuan Ping*, Guping Tang*
Advanced Functional Materials, (2014) - Cover Article

Engineering multifunctional capsules through the assembly of metal–phenolic networks
Junling Guo, Yuan Ping, Hirotaka Ejima, Karen Alt, Mirko Meissner, Joseph J Richardson, Yan Yan, Karlheinz Peter, Dominik von Elverfeldt, Christoph E Hagemeyer, Frank Caruso*
Angewandte Chemie International Edition, (2014) - Cover Article
(Profited by:
- ChemViews Magazine: “Versatile Capsules”;
- Phys.Org:“Multifunctional microcapsules made from metals and tannic acid”;
- IDW-oline: “Maßgeschneiderte Mikrokapseln”;
- Chemie.de: “Multifunktionale Mikrokapseln aus Metallen und Gerbsäure”;
- Entrepreneur.MD: “Multifunctional microcapsules can be produced from tannic acid and metals”;
- I4U News: “Multifunctional microcapsules can be produced from tannic acid and metals”;
- Bioportfolio.com: “Summary of multifunctional microcapsules”;
- Bionity.com: “Multifunktionale mikrokapseln aus metallen und gerbsäure”;
- News-in-industry: “Maßgeschneiderte Mikrokapseln”;
- Business.newzs.de: “Gezielte Auswahl der Metall Bausteine ermöglicht breite Anwendung in der medizinischen Bildgebung”;

Convective polymer assembly for the deposition of nanostructures and polymer thin films on immobilized particles
Joseph J Richardson, Mattias Björnmalm, Sylvia T Gunawan, Junling Guo, Kang Liang, Blaise Tardy, Shota Sekiguchi, Ka Fung Noi, Jiwei Cui, Hirotaka Ejima, Frank Caruso*
Nanoscale, (2014)
Complex oxide–noble metal conjugated nanoparticles
Junling Guo, Yao‐De Chiou, Wen‐I Liang, Heng‐Jui Liu, Ying‐Jiun Chen, Wei‐Cheng Kuo, Chih‐Ya Tsai, Kai‐An Tsai, Ho‐Hung Kuo, Wen‐Feng Hsieh, Jenh‐Yih Juang, Yung‐Jung Hsu, Hong‐Ji Lin, Chien‐Te Chen, Xue‐Pin Liao, Bi Shi, Ying‐Hao Chu*
Advanced Materials, (2013)

One-step seeding growth of controllable Ag@Ni core–shell nanoparticles on skin collagen fiber with introduction of plant tannin and their application in high-performance microwave absorption
Junling Guo, Xiaoling Wang, Penglong Miao, Xuepin Liao, Wenhua Zhang, Bi Shi
Journal of Materials Chemistry A, (2012) - Cover Article

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Angew. Chem. Int. Ed. 2014, 53_cover pic

Full publication list can be found here: